Genomes, Comparative and Computational Genomics Career Prospects and Learning Outcome
The future of Medicine :
The applications of knowledge gained from the characterization of genomes, including Human genome holds a considerable potential for the development of new health care innovations presenting a series of highly complex scientific, economic, social and ethical issues. The characterization of all living organisms reflects the complex interactions between their genetic make-up, their environment and the long history of the milieu in which they are raised. Genomics knowledge has provided that the biological functions result from this interplay is explained in term of biochemical mechanisms, which in turn reflect the activities of the genes which regulate them. The knowledge of metabolic pathway has helped the biomedical researchers for the analysis of disease mechanism at the molecular level and genes in particular. The sum total of the genetic information of an individual which is encoded in structure of deoxyribonucleic acid DNA is called genome and the study of genomes is known as genomics .After the successful completion of genome projects next challenge augmented for researchers is into functional genomics that aims to characterize different genes which constitute genomes and their variability of action leading to identify how genes are regulated and interact with each other or with environment to control the complex biochemical functions of living organisms, or in health and disease. Further developments in the field of genomics would decipher new insights into the mechanisms of human and animal development and ageing leading to start to unravel our genetic roots which help to understand the relationships between and within the species. The potential of genomics for healthcare is that the information generated by genomics has major benefits for the prevention, diagnosis and management of many diseases which hitherto have been difficult or impossible to control.
Thus rapid progress in genome science and a glimpse into its potential applications have spurred observers to predict that biology will be the foremost science of the 21st century. Technology and resources generated by the Human Genome Project and other genomics research are already having a major impact on research across the life sciences. The potential for commercial development of genomics research presents U.S. industry with a wealth of opportunities, and sales of DNA-based products and technologies in the biotechnology industry are projected to exceed $45 billion or more.
BII with its mission of knowledge dissemination in upcoming applied fields of life sciences has launched E-Learning program on Genomes, Comparative and Computational Genomics with an objective to provide in-depth knowledge base in the area of new specialized field of genomics.
Aims and Objectives :
The main objective of Genomics course is to understand the architecture of genetic variation in and among populations, which has wide applications in biomedical sciences. The course would endow the participants with the tools required to understand the various genomics approaches and tools required to understand insights of the organism.
This course provides an introduction to the field of genomics. It covers the structure of the human genome, and the strategies that were used to map and sequence the genome, and details how genomic sequence information is utilized for pharmacogenomics, drug discovery and diagnostics. The course would also introduce post-genomics technologies such as bioinformatics, functional genomics and proteomics .Other objectives of the course are mentioned below:
• Explain the composition and structure of the human genome
• Understand the concept of Pharmacogenomics
• Specify how genomics information is used in the area of drug development
• Specify the different methods for collating and analyzing the mass of information resulting from the human genome sequence
• Describe how the function of novel genes is determined
• Explain the proteomics approach that will map and characterize all of the proteins encoded by the genome.
Benefits of the Course :
The participants after the completion of the course would be able to
• To enable students from a broad range of disciplines to acquire and apply knowledge and understanding of the Genome Revolution and its growing impact on their distinct fields.
• To cultivate in students the interdisciplinary perspectives necessary to address current and future implications of genomics for health, science and society.